The below link is to a spec sheet for the Siemens SC-44, which is the probable candidate for new diesels - I'd assume their marketed 95% reductions particulate and 89% for NOx compared to Tier 0 is largely accurate, despite the T's F40s and GP40s being Tier 0+.Beyond that, they are 4400hp locomotives, compared to 3000hp, which partially goes to acceleration, and are rated for much higher top speeds.
(I believe the F40s and GPs max out at 103mph, but are limited in service to 79mph. this shouldn't really matter - most of the system is a 79mph max due to track and coach speeds. Afaik, even on the NEC, the bilevels aren't rated to more than 90mph.)
Fuel efficiency numbers aren't published anywhere I can find, but reliability wise, they're all on their second rebuild... the oldest GPs are from the 70s so are 50 years old. The youngest F40s are all 30+. Theres only so much rebuilding they can do before its better to buy something new, as the latest F40 rebuilds were only supposed to buy 10 years, 20 with additional major component overhauls. The early ones are already halfway though that window. The GPs didn't get full second rebuilds, just "heavy maintenance" done in house, so they're probably even more so running on borrowed time.
Worth keeping in mind too that overhauls aren't cheap - in 2019, the T paid 79M to overhaul the 37 F40s, 2M each. The HSP46s cost 6M each to buy in 2013, though they too are up for overhaul. Leaving aside the basis year problem, new chargers would probably run 10-15M, depending on the number of option units included/exercised.