Sure it would. The 71 draws more daily riders than SL2 + Silver Line Way short-turns on the Transitway. And takes over a half-hour at peak to get between Harvard and the Square and regularly gets stuck in traffic. Single fare out of Harvard, 1 stop in the reverse-commute direction, and transfer to Green Line beats the bus every time, with 1-1/2 times the frequencies. Why wouldn't the north end of the E's run end up clocking in at about 70-75% of the E branch's dedicated ridership with those advantages coupled with the exploding growth in North Cambridge and East Watertown. For one, you currently cannot get to Watertown at all from North Cambridge without slogging it to Harvard and getting on the bus. Watertown may as well be on the Moon for anyone in Somerville or anywhere on the 77.
You can't compare it with Brighton. Brighton's population center has always had easy one-seat access to Watertown. It's a mature transit route. Everything north, northwest, and northeast of Harvard never has. And there are a fucklot of people who live there. Many of them
[*North Cantabrigian raises hand*] need to get to the Mall sometimes and hate the senselessness of having to drive such a short crow-flies distance in the car or walk an hour on Nonantum Rd. within inches of Formula One-speeding traffic to get there because there's no direct way. Watch the Minuteman-level utilization of the Greenway when it reaches Alewife on this ROW. There's a commuter market here that'll saturate whatever mode you feed it, including sneakers and bikes, because it opens up a high-demand direct route that has never ever existed before.
This route isn't in competition with the 57. It's faster from downtown because of the grade separation, and taps a whole new audience by making the impossible possible. Brighton needs a separate solution. It doesn't need to pooh-pooh Cambridge's/Somerville's/CBD's good transit solution to Watertown.