Kowloon still packs them in, and won't be going anywhere anytime soon. I believe Prince still does brisk business as well, but haven't been in there in a few years.
Hilltop probably should've opened a comedy club.
Prince's business dipped for a bit, but seems to have recovered and held strong for a while now.
Rt 1 is definitely losing its character, though, but that is certainly nothing new. It's been happening since before I was born, and my family has lots of memories of other businesses on Rt 1, along with our own, which had both unique style and service but were replaced with sterile crap.
The Palace -> Lowes
Weylu's -> In limbo for redevelopment
Orange Dinosaur -> Still there... for now
Santoro's Subs (original location) -> Walgreens
Some amusement park or zoo -> Saugus High School (or near it)
Kowloon -> Going strong
Hockey Town -> Still there... for now
Hilltop -> In limbo for redevelopment
Border Cafe -> In limbo for redevelopment
Drive-in Movie Theatre -> Strip mall and Eastern Bank Building
Red Barn (?) -> Kelly's
Russo's Candies -> SaugusBank
Prince Pizza -> Going strong
Caruso Diplomat -> Strip mall anchored by Trader Joe's
Chickland -> Don't even know where this was
And there were a number of places that I've seen black and white photos of where there were really unique restaurant concepts.