Technical feasibility is always: "easy, given unlimited budget". Daylight the thing and rebuild.
Freeze the earth above it and re-excavate. Excavate slurry walls and span with bridgework.
All kinds of neat techniques exist.
You're asking to free up, what, 40 square feet of space? (10 columns 2'x2'?). Call it 90 square feet (assuming each column is a dead space 3'x3').
Everyone "knows" that by the 1920s the standard was centerline pillars and column-free boarding. Then by the 1960s (BART & WMATA) it was column-free everything. But I can't think of anybody who has ever thought it good to remove columns short of a full replacement (e.g. new Harvard Sq, new WTC)
Each person takes up about 3 square feet. The best/cheapest way to permanently add 90 square feet's worth of un-crowding GC is to permanently shift 30 connecting riders per cycle to some other connecting point. Building Blue @ MGH would probably do that for the same $ as whatever best-case technical solution is at GC.